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Events for October 5, 2016

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8:15 am

Welcome to Virginia Tech, Virginia Tech President Tim Sands, PhD

October 5, 2016 @ 8:15 am - 8:25 am
Tim Sands

                   

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8:40 am

Dynamic Regulation of Signaling Pathways in Dopamine Neurons: The Intracellular Actions of Amphetamines, Susan Amara, PhD

October 5, 2016 @ 8:40 am - 9:05 am
Susan Amara, PhD

Susan Amara, PhD, Scientific Director, Division of Intramural Research Program and Chief, Laboratory of Molecular and Cellular Neurobiology, National Institute of Mental Health, National Institutes of Health -- Neurotransmitter transporters present at the plasma membrane are the primary targets for psychostimulant drugs of abuse and for drugs such as methylphenidate and amphetamines, which are used

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9:05 am

Genetic Basis of Major Depression – Jonathan Flint, MD

October 5, 2016 @ 9:05 am - 9:30 am
Jonathan Flint

Professor-in-Residence, Department of Psychiatry and Biobehavioral Sciences, UCLA David Geffen School of Medicine
Senior Scientist, Center for Neurobehavioral Genetics, UCLA Semel Institute for Neuroscience and Human Behavior

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9:30 am

Industry Perspectives: Bradley Miller, MD/PhD and Michael Wood, PhD

October 5, 2016 @ 9:30 am - 10:30 am
panel_industry

Presenters will share their perspective on the development of therapeutics in precision neuroscience from their industry experience.

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10:30 am

Break

October 5, 2016 @ 10:30 am - 11:00 am
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11:00 am

A Quantitative Signature of Change in Impulsivity: Toward Prediction of Clinical Response, Warren Bickel, PhD

October 5, 2016 @ 11:00 am - 11:25 am
Warren Bickel, PhD

Warren Bickel, PhD, Virginia Tech Carilion Behavioral Health Research Professor and Professor of Psychology, Virginia Tech-- Predicting response to treatment is an important goal of science and would contribute substantially to precision medicine.  One type of change, referred to as rate (or baseline) dependence, has a quantitative signature that may be exploited to predict who

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11:25 am

Serotonin, Impulsivity, and Cue Reactivity: Preclinical and Clinical Studies, F. Gerard Moeller, MD

October 5, 2016 @ 11:25 am - 11:50 am
Gerard Moeller, MD

 F. Gerard Moeller, MD, Professor, Department of Psychiatry, Pharmacology and Toxicology, and Neurology, Virginia Commonwealth University (VCU); Director, VCU Institute for Drug and Alcohol Studies and Director of Addiction Medicine; Director, C. Kenneth and Dianne Wright Center for Clinical and Translational Research; Associate Vice President for Clinical Research -- Impulsivity has been linked to drug

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1:00 pm

Engineering Viral Vectors for Targeted Therapeutics and In Vivo Circuit Connectomics, Tomas Bjorklund, PhD

October 5, 2016 @ 1:00 pm - 1:25 pm
Tomas Bjorklund, PhD

Tomas Bjorklund, PhD, Assistant Professor, Wallenberg Neuroscience Center, Lund University, Lund, Sweden -- In situ neuromodulation has seen significant developments with the rapid recent improvements in optogenetics, chemogenetics and genome editing. However, as these tools progress towards clinical applications, there is an urgent need to develop both the tools to target specific neuronal circuits in the

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1:25 pm

A New Approach to Rapid Neurotransmitter Measurement in Humans During Active Cognition, P. Read Montague, PhD

October 5, 2016 @ 1:25 pm - 1:50 pm
Read Montague, PhD

P. Read Montague, PhD, Virginia Tech Carilion Vernon Mountcastle Research Professor and Professor of Physics, Virginia Tech --

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1:50 pm

SorCS2 Regulates Dopaminergic Wiring and BDNF-Dependent Plasticity, Anders Nykjaer, MD/PhD

October 5, 2016 @ 1:50 pm - 2:15 pm
Anders Nykjaer, MD/PhD

Anders Nykjaer, MD/PhD, Professor of Medical Biochemistry; Director of the Lundbeck Foundation Research Centre MIND; Danish Research Institute of Translational Neuroscience - DANDRITE; Nordic - EMBL Partnership of Molecular Medicine; Aarhus University, Denmark -- It is well accepted that psychiatric disorders commonly result from developmental deficits superimposed acute changes in synaptic plasticity. Multiple studies have

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2:15 pm

Break

October 5, 2016 @ 2:15 pm - 2:45 pm
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2:45 pm

Insulin Resistance and Neurodegeneration: Novel Mechanisms and Therapeutic Implications, Suzanne Craft, PhD

October 5, 2016 @ 2:45 pm - 3:10 pm
dr-suzanne-craft-3

Suzanne Craft, PhD, Professor of Geriatric Medicine, Director, NIA P30 Alzheimer's Disease Core Center, Co-Director, Sticht Center for Healthy Aging and Alzheimer's Prevention, Wake Forest University Medical School

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3:10 pm

Synaptic Biomarkers: Promise and Perils for Identifying and Using Them to Optimize Neuronal Health, Greg Valdez, PhD

October 5, 2016 @ 3:10 pm - 3:35 pm
Greg Valdez, PhD

Assistant Professor, VTCRI; Assistant Professor, Virginia Tech School of Biological Sciences, College of Science The lack of biomarkers is a major roadblock in identifying and testing therapeutics for neurological disorders.  In common among neurological diseases is the early and progressive degeneration of synapses, that inevitably cause neuronal dysfunction.  Hence, the identification of molecules altered during

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3:35 pm

Amyloid-β and Tau: the Trigger and Bullet in Alzheimer’s Disease Pathogenesis, George Bloom, PhD

October 5, 2016 @ 3:35 pm - 4:00 pm
George Bloom, PhD

George Bloom, PhD, Professor of Biology and of Cell Biology, University of Virginia -- The well known behavioral symptoms of Alzheimer’s disease (AD) result from two processes that compromise brain function: synaptic dysfunction and loss among neurons that mediate memory and cognition, and the death of those neurons. It follows naturally that defining the causes

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4:00 pm

Toward Understanding Differential Risk for Intellectual Disability: An Experimental Approach, Craig Ramey, PhD

October 5, 2016 @ 4:00 pm - 4:25 pm
Craig Ramey, PhD

Craig Ramey, PhD, Professor and Distinguished Research Scholar of Human Development, VTCRI; Professor, Virginia Tech School of Psychology, College of Science; and Professor of Pediatrics, Virginia Tech Carilion School of Medicine -- Social and economic status are strongly positively related to health and cognitive development. Under educated and economically poor families have children who are

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4:30 pm

Poster Sessions, VTCRI Floor One

October 5, 2016 @ 4:30 pm - 5:30 pm
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